四柱性大動脈弁:特徴,関連する構造的心血管異常,および臨床結果
Michael Y C Tsang1, Muaz M Abudiab1, Naser M Ammash1
1From Divisions of Cardiovascular Diseases (M.Y.C.T., N.M.A., V.T.N., P.A.P.) and Anatomic Pathology (W.D.E.), Mayo Clinic, Rochester, MN; and Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ (M.M.A., T.Z.N.).
Circulation
|December 5, 2015
まとめ
クアドリクスピッド大動脈弁 (Quadricuspid aortic valve,QAV) は希少な欠陥であり,患者の0. 006%に発生する. 大動脈の膨張や嘔吐などの関連疾患は一般的ですが 長期的な生存率は優れています
科学分野:
- 心臓病科
- 生まれつき の 心臓 障害
- エコカルディオグラフィー
背景:
- 四柱性大動脈弁 (QAV) は珍しい先天性心不全である.
- 罹患率,それに関連する異常,そして長期的な結果を理解することは極めて重要です.
研究 の 目的:
- QAVの頻度を大きなエコーカルディオグラフィーデータベースで決定する.
- QAV患者の関連心血管異常を特徴付ける.
- QAVと診断された人の長期的なアウトカムについて説明してください.
主な方法:
- 大規模なエコーカルディオグラフィのデータベースを遡って分析した.
- 1975年1月1日から2014年3月14日の間にQAVと診断された患者を含む.
- QAV型,関連する心臓異常,および患者の追跡データに関する評価
主要な成果:
- QAVは50人の患者で診断され,0. 006%の頻度を示した.
- 大動脈の膨張 (29%) と中等から重度の大動脈吐 (26%) が一般的であった.
- 他の心臓異常は患者の32%に存在し,8人の患者は主に重度の嘔吐のために大動脈弁の手術を必要とした.
結論:
- QAV患者では,大動脈の膨張やその他の構造的な心異常が比較的一般的です.
- 主な血液動力学的問題であり,手術用である.
- QAV患者の長期生存率は5年後に91. 5%,10年後に87. 7%と良好です.
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