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Updated: Mar 29, 2026

Using Human Induced Pluripotent Stem Cell-derived Intestinal Organoids to Study and Modify Epithelial Cell Protection Against Salmonella and Other Pathogens
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インタールイキン-22は腸幹細胞媒介の上皮再生を促進する

Caroline A Lindemans1,2, Marco Calafiore1, Anna M Mertelsmann1

  • 1Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.

Nature
|December 10, 2015
PubMed
まとめ

生まれながらのリンパ性細胞 (ILC) は,損傷後の腸内皮質再生を促進し,インタールイキン22 (IL-22) を生成する. IL-22は腸の幹細胞 (ISC) を直接活性化し,その成長を促進し,組織修復を促します.

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