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Synthesis of Bimetallic Pt/Sn-based Nanoparticles in Ionic Liquids
Published on: August 23, 2018
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非対称なエポキシデーションと硫酸化のための新しい二金属触媒の設計
Sukalyan Bhadra1, Matsujiro Akakura2, Hisashi Yamamoto1
1Molecular Catalyst Research Center, Chubu University , 1200, Matsumoto-cho, Kasugai, Aichi 487-8501, Japan.
Journal of the American Chemical Society
|December 10, 2015
まとめ
新しいキラルリガンドは,アルコールとフェノルの選択的エポキシデーションのためのチタン触媒を可能にします. この突破はまた,硫化物の非対称的酸化を達成し,以前はアクセス不可能なキラル硫化物を生み出します.
科学分野:
- 有機金属化学
- 非対称な触媒
- 有機合成
背景:
- チラルのリガンドは,ステレオ選択的合成に不可欠です.
- タイタニウム複合体は有機変異の効果的な触媒である.
- 酸化に挑戦する新しい触媒システムの開発は,継続的な需要です.
研究 の 目的:
- 8キノリノール基のキラル結合リガンドの新種を開発する
- 誘導された二核チタニウム複合体の触媒活性を調べる
- 新しい地域とステレオ選択的酸化反応を探求する.
主な方法:
- 8-キノリノール基の新型キラル結合リガンドの合成.
- 二核のチタン複合体の形成と特徴付け
- エポキシデーションと酸化反応における触媒システムの適用
主要な成果:
- 二核のチタン複合体は,原始的および三次的ホモアリルアルコールをエポキシド化するのに高い地域およびステレオ選択性を示した (最大98% ee).
- 2-アリルフェノールの非対称なエポキシデーションの最初の例 (最大92% ee) が達成された.
- γ-ヒドロキシプロピル硫化物の非対称な酸化を成功裏に促進し,キラル硫化物 (最大95% ee) としました.
結論:
- チラルリガンドの新種とそのチタン複合体は 強力な触媒システムを提供します
- 開発された触媒は,有価なキラル化合物の効率的かつ選択的な合成を可能にします.
- この研究は,有機化学における非対称性酸化方法の範囲を拡大する.
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