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Updated: Mar 29, 2026

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
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L-RNA アプタマーを用いたマイクロRNA 処理の特定の阻害

Jonathan T Sczepanski1, Gerald F Joyce1

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|December 15, 2015
PubMed
まとめ

研究者はマイクロRNA (miRNA) 処理のアプタマー阻害剤を開発した. これらのaptamiRは前駆体miRNAと結合し,Dicer酵素の活性を阻害し,成熟したmiRNAの形成を防止し,新たな治療戦略を提供している.

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