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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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RNAポリメラーゼII関連因子1は,停止したRNAポリメラーゼIIの放出とリン酸化を調節する

Ming Yu1, Wenjing Yang2, Ting Ni3

  • 1Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY 10065, USA.

Science (New York, N.Y.)
|December 15, 2015
PubMed
まとめ

遺伝子調節に不可欠なPol IIの放出を一時停止させるには,新しい要因が含まれる. 陽性転写延長因子b (P-TEFb) はPAF1複合体 (PAF1C) を誘導し,その後CDK12を誘導し,協力的メカニズムを明らかにする.

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