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Updated: Mar 27, 2026

Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study
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イソプロテレノールは,ライアノジン受容体の急速な移動をブリッジングインテグレーター1 (BIN1) - オーガナイズドダイアッドに促進する

Ying Fu1, Seiji A Shaw1, Robert Naami1

  • 1From Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (Y.F., S.A.S., R.N., C.L.V., W.A.B., T.H.); Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (X.G.); and Departments of Medicine, Cedars-Sinai Medical Center and UCLA, Los Angeles, CA (T.H.).

Circulation
|January 7, 2016
PubMed
まとめ

ブリッジングインテグレーター1 (BIN1) は,カルシウム処理を改善するために心臓細胞の重要なタンパク質を組織します. 心不全でBIN1が低下すると,このプロセスが損なわれ,不律が起こります.

キーワード:
BIN1タンパク質心不全膜マイクロドメイン心臓のミオサイトアドレナゲン,ベータ受容体ライオジン受容体2 マウス

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