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Updated: May 14, 2026

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
08:51

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling

Published on: June 25, 2015

イーストのTATA結合因子TFIIDをコードする遺伝子SPT15は,体内での正常な転写開始には必要である

D M Eisenmann1, C Dollard, F Winston

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.

Cell
|September 22, 1989
PubMed
まとめ

TATA結合因子TFIIDをコードするSPT15遺伝子の変異が遺伝子転写を変化させることが判明しました. この重要な転写因子は,酵母菌の成長,交配,および胞子形成に不可欠であり,多数の遺伝子に影響を与えます.

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Efficient Transcriptionally Controlled Plasmid Expression System for Investigation of the Stability of mRNA Transcripts in Primary Alveolar Epithelial Cells10:49

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Transcription Factors02:16

Transcription Factors

Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
Transcription Factors02:16

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Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
Bacterial Transcription01:53

Bacterial Transcription

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Transcription Initiation

Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
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General Transcription Factors01:30

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Transcription in Prokaryotes

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