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Updated: Mar 27, 2026

Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals
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Fluorescence-based Neuraminidase Inhibition Assay to Assess the Susceptibility of Influenza Viruses to The Neuraminidase Inhibitor Class of Antivirals

Published on: April 15, 2017

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ANP32Aの種差が,インフルエンザAウイルスポリメラーゼ宿主制限の基礎となっている

Jason S Long1, Efstathios S Giotis1, Olivier Moncorgé2

  • 1Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London W2 1PG, UK.

Nature
|January 8, 2016
PubMed
まとめ

鳥インフルエンザウイルスのポリメラーゼは,宿主タンパク質ANP32Aの差異により,ヒト細胞で闘う. ANP32Aを改変することで 鳥インフルエンザウイルスの複製が可能になり 抗ウイルス標的として強調されます

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