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Updated: Apr 16, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
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Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

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ペプチドマイクロアレイを用いて,アポトーシスを誘発する活動に対するプレミRNA-155結合ペプチドのスクリーニング

Jaeyoung Pai1, Soonsil Hyun2, Ji Young Hyun1

  • 1National Creative Research Center for Biofunctional Molecules, Department of Chemistry, Yonsei University , Seoul 03722, Korea.

Journal of the American Chemical Society
|January 16, 2016
PubMed
まとめ

研究者らは,がんにおける重要な腫瘍遺伝子のマイクロRNA-155 (miRNA-155) 処理を阻害する2つのペプチドを特定した. これらのペプチド阻害剤は,Dicerの活性を阻害し,アポトーシスを誘発することによって,癌細胞の死滅を促進します.

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