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Updated: Mar 27, 2026

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
07:51

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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アストロサイトは,ヘヴィン経由でNRX1αとNL1をブリッジすることで,タラモコルチカルシナプスを組み立てる

Sandeep K Singh1, Jeff A Stogsdill1, Nisha S Pulimood2

  • 1Department of Cell Biology, Duke University Medical Center, Durham, NC 27710.

Cell
|January 16, 2016
PubMed
まとめ

神経細胞が分泌するヘビンタンパク質はニューレキシン-1αとニューロリギン-1Bを橋渡しし,重要なシナプス結合を形成する. この発見は,アストロサイトがどのようにシナプス形成を制御し,神経発達障害に影響を与えるかを明らかにしています.

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Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments06:53

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