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Updated: Mar 27, 2026

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エボラウイルスのグリコタンパク質は,その内分泌受容体Niemann-Pick C1に結合する

Han Wang1, Yi Shi2, Jian Song1

  • 1CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Cell
|January 16, 2016
PubMed
まとめ

エボラウイルスの宿主細胞への侵入は,Niemann-Pick C1 (NPC1) タンパク質がウイルスグリコタンパク質 (GP) に結合することを含む. この構造研究は,NPC1結合が膜融合をどのように誘発し,抗ウイルス治療の標的を提供することを明らかにしています.

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