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Updated: Mar 26, 2026

Author Spotlight: Optimized Protocol for Detecting Antigen-Specific T Cells in Mouse Lungs Using Tetramers
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Author Spotlight: Optimized Protocol for Detecting Antigen-Specific T Cells in Mouse Lungs Using Tetramers

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主要ヒストコンパティビリティ複合体Eによって制限された広範に標的化されたCD8+T細胞応答

Scott G Hansen1, Helen L Wu1, Benjamin J Burwitz1

  • 1Vaccine and Gene Therapy Institute and Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.

Science (New York, N.Y.)
|January 23, 2016
PubMed
まとめ

修飾されたサイトメガロウイルスベクターによるワクチン接種は,メジャー・ヒストコンパティビリティ・コンプレックスE (MHC- E) によって制限される多様なT細胞反応を誘発する. これらのMHC- E- 制限されたCD8 ((+)) T細胞反応は,持続的なウイルス感染症に対して優れた有効性を提供する可能性があります.

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