関連する実験動画

Updated: May 7, 2026

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome
11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Published on: March 2, 2018

7.7K

MeCP2を過剰に発現するトランス遺伝子類のサルにおける自閉症のような行動と生殖系統の伝播

Zhen Liu1, Xiao Li1, Jun-Tao Zhang1

  • 1Institute of Neuroscience, CAS Key Laboratory of Primate Neurobiology, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China.

Nature
|January 26, 2016
PubMed
まとめ

メチル-CpG結合タンパク質2 (MeCP2) を過剰に発現する遺伝子組み換え猿は 社会的欠陥や繰り返しの動きを含む 自閉症のような行動を示します この研究は,MeCP2に関連する脳疾患をモデル化するために,ヒト以外の霊長類の有用性を示しています.

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