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Updated: Mar 26, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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カチオニク・キラル・フッ化オキサボロリジン より強力で,高度にエナチオセレクティブなサイクル添加反応のための第2世代の触媒

Karla Mahender Reddy1, Eswar Bhimireddy1, Barla Thirupathi1

  • 1Department of Chemistry and Chemical Biology, Harvard University , Cambridge, Massachusetts 02138, United States.

Journal of the American Chemical Society
|January 27, 2016
PubMed
まとめ

研究者らは,ダイエルス-アルダー反応のエナチオセレクティブ触媒を強化する新しいキラルオキサボロリジニウム触媒を開発した. これらの触媒は,低負荷を用いて収穫量とエナチオ選択性を改善し,大規模合成のために容易に回収できます.

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