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Updated: Mar 26, 2026

Monitoring Leucine-Rich Repeat Containing 8 Channel (LRRC8/VRAC) Activity Using Sensitized-Emission Förster Resonance Energy Transfer (SE-FRET)
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NEK7は,カリウム流出の下流のNLRP3活性化の重要な媒介物である

Yuan He1, Melody Y Zeng1, Dahai Yang1,2

  • 1Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Nature
|January 28, 2016
PubMed
まとめ

NEK7はNLRP3炎症体の活性化に不可欠なタンパク質であり,炎症性疾患における炎症性カスパース-1の活性化とIL-1βの放出を制御するために,カリウム流出の下流に作用する.

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