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Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart
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Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart

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衰え て いる 心臓 は ケトン 体 を 燃料 と し て 用いる

Gregory Aubert1, Ola J Martin1, Julie L Horton1

  • 1From Cardiovascular Metabolism Program, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL (G.A., O.J.M., J.L.H., L.L., R.B.V., T.C.L., S.J.G., P.A.C., D.P.K.); Departments of Medicine, Pharmacology, and Cancer Biology, Duke University, Durham, NC (T.K., D.M.M.); CECAD Research Center, Institute for Genetics, University of Cologne, Cologne, Germany (M.K.); Departments of Pharmacology and Medicine, Case Western Reserve University, Cleveland, OH (C.L.H.); College of Medicine, University of Illinois at Chicago, Chicago, IL (E.D.L.); and Department of Medicine, Washington University School of Medicine, St. Louis, MO (P.A.C.).

Circulation
|January 29, 2016
PubMed
まとめ

脂肪酸の利用量が減ると ケトンの体を使うようになります 心不全におけるこれらの代謝変化の特定は,新しい治療法につながる可能性があります.

キーワード:
脂肪酸心不全ハイパートロフィーメタボリズム分子生物学

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