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Updated: Mar 26, 2026

Monitoring Leucine-Rich Repeat Containing 8 Channel (LRRC8/VRAC) Activity Using Sensitized-Emission Förster Resonance Energy Transfer (SE-FRET)
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Monitoring Leucine-Rich Repeat Containing 8 Channel (LRRC8/VRAC) Activity Using Sensitized-Emission Förster Resonance Energy Transfer (SE-FRET)

Published on: August 9, 2024

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LRRC8タンパク質は,イオン力を感知する量調節アニオンチャネルを形成する

Ruhma Syeda1, Zhaozhu Qiu2, Adrienne E Dubin1

  • 1Department of Molecular and Cellular Neuroscience, Howard Hughes Medical Institute, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

Cell
|January 30, 2016
PubMed
まとめ

容量調節アニオンチャネル (VRAC) はLRRC8タンパク質によって形成される. 細胞プラズマのイオン強度を下げることでVRACを活性化させ,チャネルを明らかにします.

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