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Updated: Mar 26, 2026

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DNAポリメラーゼ λのフィデリティ調節のための構造メカニズム

Mu-Sen Liu1, Hsin-Yue Tsai, Xiao-Xia Liu

  • 1Institute of Biochemical Sciences, National Taiwan University , Taipei 106, Taiwan.

Journal of the American Chemical Society
|February 3, 2016
PubMed
まとめ

人間のDNAポリメラーゼラムダ (Pol λ) は,高忠実性ポリメラーゼとは異なり,独特の構成状態とMgdNTPのプリバインディングを弱める特定の水害性コアにより,中等忠実性を達成する.

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