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Updated: Mar 26, 2026

Precise Phage Mutagenesis with NgTET-Assisted CRISPR-Cas Systems
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CRISPR関連RNaseによるファージトランスクリプトの退化により,CRISPR-Cas型免疫が可能になる

Wenyan Jiang1, Poulami Samai1, Luciano A Marraffini1

  • 1Laboratory of Bacteriology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Cell
|February 9, 2016
PubMed
まとめ

タイプIII-AのCRISPR-Casシステムは,RNAを標的とし,ウイルスのトランスクリプトを劣化させ,ファグに対するプロカリオット免疫を強化します. このRNAの分解は 強力な防御に不可欠です 特にDNAのクリアランスが遅い場合です

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