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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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1,2-サイクロヘキサディエンの窒素サイクル添加物

Joyann S Barber1, Evan D Styduhar1, Hung V Pham1

  • 1Department of Chemistry and Biochemistry, University of California , Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|February 9, 2016
PubMed
まとめ

この研究は,1,2-サイクロヘクサディエンの使用による最初の1,3-二極サイクロアディションを導入します. ニトロンとの反応は,高い選択性を持つイソキゾリジンを生成し,新しい合成経路を示しています.

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