関連する実験動画

Updated: Mar 25, 2026

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction
09:25

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction

Published on: January 9, 2015

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マグネシウムチャネルCORAの冷凍-EM構造は,ゲーティング時に対称性を破る

Doreen Matthies1, Olivier Dalmas2, Mario J Borgnia1

  • 1Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

Cell
|February 13, 2016
PubMed
まとめ

プロカリオットの重要なマグネシウムトランスポーターであるCorAは,重要な形状の変化によって開閉する. このマグネシウムイオンチャネルゲーティングメカニズムは,冷凍-EMによって明らかにされ,おそらく同様のイオンチャネルに適用されます.

キーワード:
非対称性形状の変化電子探知器イオンチャンネル膜タンパク質構造単粒子冷凍電子顕微鏡

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Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers09:54

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers

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