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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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エナチオセレクティブ・トータル・シンセシス (-) - アルストスコラリシンA

Xiao Liang1,2, Shi-Zhi Jiang1, Kun Wei1

  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, China.

Journal of the American Chemical Society
|February 17, 2016
PubMed
まとめ

研究者らは,神経幹細胞の成長を促す生物活性アルカロイドである (-) - アルストスコライシンAを合成した. この簡潔な合成は,重要な触媒反応を用いて複数のステレオセンターを効率的に確立しました.

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