発達中期の移行と動物の体プランの進化
Michal Levin1, Leon Anavy1, Alison G Cole1
1Department of Biology, Technion - Israel Institute of Technion, Haifa 32000, Israel.
Nature
|February 18, 2016
まとめ
身体計画に基づく動物集団であるフィラは,中期の発達移行期に保存された遺伝子発現によって客観的に定義され得る. この移行は初期と後期の遺伝子発現の相を結びつけ,様々な種にまたがる 線型期を潜在的に定義する.
科学分野:
- 発達生物学
- 進化生物学
- ゲノミクス
背景:
- 動物系は伝統的に異なる体型で定義される.
- フィロタイプ期は,保存された発達段階であり,いくつかのフィラの中に存在する.
- ファイラの現在の定義には客観的な基準が欠けていて,恣意的なグループ化につながります.
研究 の 目的:
- 動物族を定義するための客観的な基準を調査する.
- フィラムの定義における発達中の遺伝子発現の役割を調査する.
- 様々な動物種における 発達のトランスクリプトームを比較する.
主な方法:
- 異なる属の10種の発達のトランスクリプトームの比較分析.
- 発達中の保存された遺伝子発現パターンの識別.
- 遺伝子発現の移行と既知のフィロタイプ期間の相関
主要な成果:
- 遺伝子の発現の初期と後期は全て保存された.
- 種特有の経路を用いて,異なる"中期発達の移行"がこれらの段階を結びつけています.
- この移行は,体型形成におけるその役割を示唆するフィロタイプ期と重なり合っている.
結論:
- 成長期間の移行は,生体構造を定義する上で極めて重要です.
- この移行は,他の属の属型期間を定義するのに役立つかもしれません.
- フィラムは,発達中期の異なった遺伝子発現によって定義される.
関連する概念動画
Gastrulation
68.9K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
68.9K
Convergent Evolution
34.4K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
34.4K
Evolution of New Traits in Microbes
44
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
44
Body Planes
34.6K
Body planes in anatomy are imaginary flat surfaces used as reference points to divide the body into sections for anatomical study. These planes are essential for understanding the orientation, relationships, and spatial organization of anatomical structures.
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
34.6K
Whole Body Regeneration
4.4K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.4K
Development of the Sexual Organs in the Embryo and Fetus
4.8K
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
4.8K


