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Updated: Mar 25, 2026

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons
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Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons

Published on: November 6, 2017

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ソマティック・プロ・アポプトティック・シグナリングの逆行的な活性化によってゲートされたアクソン退化

David J Simon1, Jason Pitts1, Nicholas T Hertz1

  • 1Laboratory of Brain Development and Repair, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Cell
|February 23, 2016
PubMed
まとめ

細胞体はアクソンだけでなく アクソン退化も 積極的に制御しています 細胞体に逆行信号を誘発し,軸索の除去を開始します.

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Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death09:18

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Apoptosis01:30

Apoptosis

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The Extrinsic Apoptotic Pathway01:17

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The Intrinsic Apoptotic Pathway01:31

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Autophagic Cell Death

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Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
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Necrosis01:16

Necrosis

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
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Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
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