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Updated: Mar 25, 2026

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening
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アミノアラビノストランスファーゼ (ArnT) の構造は,脂質Aグリコシル化のための分子基盤を示唆する

Vasileios I Petrou1, Carmen M Herrera2, Kathryn M Schultz3

  • 1Department of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA.

Science (New York, N.Y.)
|February 26, 2016
PubMed
まとめ

グラム陰性細菌におけるポリミキシン耐性にとって重要な酵素であるArnTの構造的な洞察は,それが細菌の外膜をどのように変化させるかを明らかにする. このメカニズムの理解は 多剤耐性感染症に対する新しい戦略の開発に不可欠です

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