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染色体近隣の破壊による原発がん遺伝子の活性化

Denes Hnisz1, Abraham S Weintraub1,2, Daniel S Day1

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|March 5, 2016
PubMed
まとめ

プロト・オンコゲンは 隔離された近隣の 重要な染色体構造の 破壊を通して オンコゲンになることができます これらの境界を突破する遺伝的変異は 腫瘍遺伝子を活性化し 癌の発生を促します

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