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多複合タンパク質-DNAのクロスリンク:転写開始部位の選択における精査

Jared T Winkelman1, Irina O Vvedenskaya2, Yuanchao Zhang3

  • 1Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA. Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA. Waksman Institute, Rutgers University, Piscataway, NJ 08854, USA. Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53705, USA.

Science (New York, N.Y.)
|March 5, 2016
PubMed
まとめ

バクテリアの転写開始には,RNAポリメラーゼが開始部位を選択することが含まれます. この研究は,RNA合成が始まる前に"差別化"要素がサイト選択とDNAスクランジングを開始することを明らかにしています.

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