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Updated: Mar 24, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
10:37

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Published on: August 27, 2013

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PKAの活性化により,メゼンキマから上皮への移行と腫瘍発起能力の喪失が起こる

Diwakar R Pattabiraman1, Brian Bierie1, Katharina Isabelle Kober1

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|March 5, 2016
PubMed
まとめ

タンパク質キナーゼA (PKA) の活性化によるメゼンキマから上皮への移行 (MET) を誘導することで,がん幹細胞を排除することができる. このアプローチは腫瘍を誘発する細胞を再プログラムし 分化を促進し 癌の再発と転移を 誘発する能力を低下させます

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