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Updated: Mar 24, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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ネイティブ化学結合におけるペプチジルプロリルチオエステルの内部活性化

Yue Gui1, Lingqi Qiu1, Yaohao Li1

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University , 38 Xueyuan Road, Haidian District, Beijing 100191, China.

Journal of the American Chemical Society
|March 17, 2016
PubMed
まとめ

この研究は,ネイティブ化学結合 (NCL) でプロリルチオエステルを使用したペプチド合成の改良された方法を導入しています. 新しい内部活性化プロトコルは,これらの挑戦的な結合の反応性を高め,効率的なペプチド結合形成を可能にします.

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