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Updated: Mar 24, 2026

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice
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プロスタグランジンE2は,先天性リンパ性細胞-IL-22軸を通して全身の炎症を抑制する

Rodger Duffin1, Richard A O'Connor1, Siobhan Crittenden1

  • 1Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK.

Science (New York, N.Y.)
|March 19, 2016
PubMed
まとめ

EP4受容体を通じたプロスタグランジンE2 (PGE2) のシグナル伝達は,全身の炎症の制御に不可欠である. この経路は,先天性リンパ性細胞 (ILC) がインタールイキン-22 (IL-22) を生成することを促進することによって,腸壁の整合性をサポートします.

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