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持続的な炎症が肝臓のメバロナート経路に及ぼす影響は,高血糖症に起因する

Daniel Okin1, Ruslan Medzhitov2

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Cell
|March 22, 2016
PubMed
まとめ

持続的な炎症は,肝臓のグルコース生成を増加させ,血糖を上昇させます. これは,CYP7A1の抑制によって発生し,RHO関連タンパク質キナーゼの活性化とグルコースホメオスタシスの変化を引き起こします.

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