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Updated: Mar 23, 2026

An Alternative Culture Method to Maintain Genomic Hypomethylation of Mouse Embryonic Stem Cells Using MEK Inhibitor PD0325901 and Vitamin C
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哺乳類の胚性幹細胞におけるN(6) -アデニンのDNAメチル化

Tao P Wu1, Tao Wang1, Matthew G Seetin2

  • 1Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, Connecticut 06520, USA.

Nature
|March 31, 2016
PubMed
まとめ

研究者らはマウス幹細胞の 新しいDNA変異であるN(6) メチラデニンを発見した. この発見は,特に若いLINE-1トランポゾンとX結合遺伝子の表遺伝子静止におけるその役割を明らかにする.

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