甲状腺機能障害
Simone De Leo1, Sun Y Lee1, Lewis E Braverman1
1Endocrine Unit, Fondazione IRCCS Cà Granda, Milan, Italy (S De Leo MD); Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy (S De Leo); and Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA (S De Leo, S Y Lee MD, Prof L E Braverman MD).
Lancet (London, England)
|April 4, 2016
まとめ
甲状腺機能過剰症は 甲状腺ホルモンの過剰生産を伴い,甲状腺毒性症は 臨床的状態である. グレイブズ病と毒性結節性腸は一般的な原因で,それぞれに様々な治療方法があります.
科学分野:
- 内分泌学
- 内科 医学
- 甲状腺科
背景:
- 甲状腺機能不全は 甲状腺ホルモンの過剰な合成と分泌によって定義されます
- 甲状腺毒性症は,どの源からでも循環する甲状腺ホルモンの上昇による臨床的症候群を記述する.
- グレイブズ病と毒性結節性腸は 甲状腺機能過剰症の主な病因である.
研究 の 目的:
- 甲状腺機能低下と 甲状腺毒性症を区別するために
- 甲状腺毒性の一般的な原因と治療戦略を概説する.
- 甲状腺機能過剰症の管理における特別な考慮事項に対処する.
主な方法:
- 甲状腺症と甲状腺毒性症に関する既存の文献のレビュー
- 共通の病因因子の分析
- 異なる甲状腺疾患の治療方法の比較
主要な成果:
- 甲状腺機能低下の主な原因は グラブス病と毒性結節性です
- グレイブス 病 の 治療 に は,抗甲状腺 薬,放射性 ヨウ素,または 手術 が 含ま れ ます.
- 抗甲状腺薬は,再発率のため,有毒な結節性で長期使用が制限されています.
結論:
- 甲状腺毒性症の管理は病因学によって異なるが,Graves病と毒性結節性の治療には異なるアプローチが用いられる.
- 甲状腺毒性症の症状緩和にはベータブロッカーは不可欠です.
- 妊婦や出産後の女性のような特殊な集団は 特別に調整された甲状腺症の治療を必要とします
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