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関連する概念動画

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Major Hormones and Their Functions01:27

Major Hormones and Their Functions

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
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Increased pulse rate01:17

Increased pulse rate

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Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
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Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.8K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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甲状腺機能障害

Simone De Leo1, Sun Y Lee1, Lewis E Braverman1

  • 1Endocrine Unit, Fondazione IRCCS Cà Granda, Milan, Italy (S De Leo MD); Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy (S De Leo); and Section of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA (S De Leo, S Y Lee MD, Prof L E Braverman MD).

Lancet (London, England)
|April 4, 2016
PubMed
まとめ
この要約は機械生成です。

甲状腺機能過剰症は 甲状腺ホルモンの過剰生産を伴い,甲状腺毒性症は 臨床的状態である. グレイブズ病と毒性結節性腸は一般的な原因で,それぞれに様々な治療方法があります.

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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科学分野:

  • 内分泌学
  • 内科 医学
  • 甲状腺科

背景:

  • 甲状腺機能不全は 甲状腺ホルモンの過剰な合成と分泌によって定義されます
  • 甲状腺毒性症は,どの源からでも循環する甲状腺ホルモンの上昇による臨床的症候群を記述する.
  • グレイブズ病と毒性結節性腸は 甲状腺機能過剰症の主な病因である.

研究 の 目的:

  • 甲状腺機能低下と 甲状腺毒性症を区別するために
  • 甲状腺毒性の一般的な原因と治療戦略を概説する.
  • 甲状腺機能過剰症の管理における特別な考慮事項に対処する.

主な方法:

  • 甲状腺症と甲状腺毒性症に関する既存の文献のレビュー
  • 共通の病因因子の分析
  • 異なる甲状腺疾患の治療方法の比較

主要な成果:

  • 甲状腺機能低下の主な原因は グラブス病と毒性結節性です
  • グレイブス 病 の 治療 に は,抗甲状腺 薬,放射性 ヨウ素,または 手術 が 含ま れ ます.
  • 抗甲状腺薬は,再発率のため,有毒な結節性で長期使用が制限されています.

結論:

  • 甲状腺毒性症の管理は病因学によって異なるが,Graves病と毒性結節性の治療には異なるアプローチが用いられる.
  • 甲状腺毒性症の症状緩和にはベータブロッカーは不可欠です.
  • 妊婦や出産後の女性のような特殊な集団は 特別に調整された甲状腺症の治療を必要とします