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Updated: Mar 23, 2026

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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癌に関連した染色体転位から派生した融合回路RNAの腫瘍性作用

Jlenia Guarnerio1, Marco Bezzi1, Jong Cheol Jeong2

  • 1Cancer Research Institute, Beth Israel Deaconess Cancer Center, Departments of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

Cell
|April 5, 2016
PubMed
まとめ

染色体トランスロケーションは,がんにおいて新しい円形RNA (circRNAs) を生み出します. これらの融合サークRNAは腫瘍の成長と治療抵抗性を促進し,新しい診断および治療標的を提供します.

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