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Updated: Mar 23, 2026

Identification of Footprints of RNA:Protein Complexes via RNA Immunoprecipitation in Tandem Followed by Sequencing RIPiT-Seq
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Identification of Footprints of RNA:Protein Complexes via RNA Immunoprecipitation in Tandem Followed by Sequencing RIPiT-Seq

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敵対的な遺伝子パラログであるUpf3aとUpf3bは,無意味な媒介によるRNA分解を制御する

Eleen Y Shum1, Samantha H Jones1, Ada Shao1

  • 1Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92103, USA.

Cell
|April 5, 2016
PubMed
まとめ

遺伝子の複製により UPF3Aが生まれました これはNMD阻害剤で トランスクリプトを安定させます UPF3Aの喪失はハイパーNMDを引き起こし,マウスの発達障害を引き起こします.

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