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関連する概念動画

Major Hormones and Their Functions01:27

Major Hormones and Their Functions

2.7K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
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Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

14.9K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
14.9K
The Pituitary Gland01:17

The Pituitary Gland

14.9K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
14.9K
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.3K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.3K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

69.7K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
69.7K
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

7.5K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
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Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
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Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

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低垂体症

Claire E Higham1, Gudmundur Johannsson2, Stephen M Shalet1

  • 1Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, UK; Centre for Endocrinology and Diabetes, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

Lancet (London, England)
|April 5, 2016
PubMed
まとめ
この要約は機械生成です。

下垂体ホルモンの欠乏症である低垂体症は,特にコルチゾール欠乏症による死亡リスクを高めます. 早期診断とホルモン補充療法が この状態の管理に不可欠です

さらに関連する動画

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

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関連する実験動画

Last Updated: Mar 23, 2026

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

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科学分野:

  • 内分泌学
  • 内科 医学

背景:

  • 低垂体症は,一つまたは複数の垂体ホルモンの欠乏を伴う.
  • アドレノコルチノトロプホルモン (ACTH) 欠乏によるコルチゾール欠乏症は,下垂体症における過剰死亡の主要な危険因子である.
  • 大人の場合,下垂体腺腫,手術,放射線療法は一般的な原因です.

研究 の 目的:

  • 垂直下垂体症の総合的な概要を提示する.
  • 診断方法と管理戦略の概要
  • ホルモン補充療法の 重要な側面を強調します

主な方法:

  • 診断には,ある種のホルモン欠乏症に対する 初期血液採取が含まれます.
  • 動的刺激検査は,ACTH,成長ホルモン,抗利尿ホルモンの欠乏を評価するために通常必要である.
  • 徐々に進化する形態では,定期的な下垂体機能の再評価が必要である.

主要な成果:

  • 代用療法にはチロキシン,ヒドロコルチゾン,性ステロイド,成長ホルモン,デスマプレシンが含まれます.
  • 急性発症では,コルチゾール欠乏症の補充が優先されます.
  • 治療は,小児から成人への移行と妊娠中に変更する必要があります.

結論:

  • 低垂体症の効果的な治療には 正確な診断と間に合ったホルモン補充が必要です
  • 最適な患者の治療結果を得るために,厳密なモニタリングと,個別化された治療調整が不可欠です.
  • 臨床医は様々な原因と 管理のニュアンスを理解することが重要です