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Updated: Mar 22, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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信号分子の相分離はT細胞受容体信号伝導を促進する

Xiaolei Su1, Jonathon A Ditlev2, Enfu Hui1

  • 1Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA. Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|April 9, 2016
PubMed
まとめ

細胞表面受容体の活性化により,シグナル伝達タンパク質が液体のようなクラスターを形成します. これらのクラスターは,シグナル出力とアクチンアセンブリを強化し,タンパク質相分離を示します.

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