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Updated: Mar 22, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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ステロイド受容体は,ダイナミッククロマチントランジションを通じてFoxA1占有を再プログラムします

Erin E Swinstead1, Tina B Miranda1, Ville Paakinaho1

  • 1Laboratory of Receptor Biology and Gene Expression, Building 41, 41 Library Drive, NCI, NIH, Bethesda, MD 20892, USA.

Cell
|April 12, 2016
PubMed
まとめ

エストロゲン受容体 (ER) とグルココルチコイド受容体 (GR) は,パイオニア因子FoxA1のゲノム分布を動的に変化させます. これは,遺伝子調節における転写因子の相互作用の柔軟なモデルを示唆している.

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