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腫瘍性KRASは,ストロマルの相互作用によって腫瘍細胞の信号伝達を調節する

Christopher J Tape1, Stephanie Ling2, Maria Dimitriadi2

  • 1The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell
|April 19, 2016
PubMed
まとめ

臓がんにおける腫瘍性KRAS (KRAS(G12D)) シグナル伝達には,腫瘍およびストロマ細胞が関与する. この相互信号は腫瘍遺伝子の効果を拡大し,腫瘍の成長と代謝に影響します.

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