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Updated: Mar 22, 2026

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
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酵素のATP反応活性調節のためのボロン酸付属分子接着剤

Kou Okuro1, Mizuki Sasaki1, Takuzo Aida1,2

  • 1Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

Journal of the American Chemical Society
|April 19, 2016
PubMed
まとめ

新しいポリマーであるGumBAnは,アデノシン三酸化物 (ATP) と結合することで,酵素活性に対するATP反応変調剤として作用する. これらのポリマーはトリプシンのような酵素を無効化しますが,ATPを追加すると,低濃度で活性を再生します.

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