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Updated: Mar 22, 2026

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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バクテリアの細胞壁合成における脂質I生成の抑制に関する構造的洞察

Ben C Chung1, Ellene H Mashalidis1, Tetsuya Tanino2

  • 1Department of Biochemistry, Duke University Medical Center, 303 Research Drive, Durham, North Carolina, 27710, USA.

Nature
|April 19, 2016
PubMed
まとめ

ミラマイシンD2によるMraY抑制に関する構造的な洞察は,大きな形状の変化を明らかにする. これらのメカニズムの理解は,細菌のペプチドグリカン生物合成を標的とした新しい抗生物質の開発を導くことができます.

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