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ゲノムDNAの標的塩基のプログラム可能な編集

Alexis C Komor1,2, Yongjoo B Kim1,2, Michael S Packer1,2

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|April 21, 2016
PubMed
まとめ

塩基編集は新種のゲノム編集技術で DNA塩基を直接変換し 二重鎖のDNAの断裂を引き起こさない. このアプローチは,最小限の不要な挿入や削除でポイント変異を効率的に修正し,遺伝子修正戦略を前進させます.

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