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Updated: Mar 22, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

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非正規のオートファギーは,死滅する細胞に対する自己炎症性,狼性反応を抑制する

Jennifer Martinez1,2, Larissa D Cunha1, Sunmin Park3

  • 1Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|April 21, 2016
PubMed
まとめ

LC3関連ファゴサイトーシス (LAP) の欠陥は,細胞クリアランスプロセスであり,全身性白血病 (SLE) に似た疾患を引き起こす可能性があります. 障害のあるLAPは,正規のオートファギーとは異なり,自己抗体と腎臓損傷につながる.

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