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グルカゴン受容体アンタゴニストのエクストラヘリカル結合部位

Ali Jazayeri1, Andrew S Doré1, Daniel Lamb1

  • 1Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK.

Nature
|April 26, 2016
PubMed
まとめ

研究者は,X線結晶学を用いて,グルカゴン受容体 (GCGR) の新しいアロステリック結合部位を明らかにした. この発見は2型糖尿病を標的とした 構造に基づく薬の設計に 新たな道を開きます

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