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Updated: Mar 21, 2026

Measurements of Physiological Stress Responses in C. Elegans
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保存された2つのヒストン・デメチラゼは,ミトコンドリアストレス誘発の長寿を調節する

Carsten Merkwirth1, Virginija Jovaisaite2, Jenni Durieux3

  • 1Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; The Glenn Center for Research on Aging, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; The Paul F. Glenn Center for Aging Research, University of California, Berkeley, Berkeley, CA 94720, USA.

Cell
|May 3, 2016
PubMed
まとめ

軽度のミトコンドリアストレスは,展開タンパク質応答 (UPR) を活性化することで寿命を長持ちさせます. この長寿経路を制御する エピジェネティック・レギュレータは 虫からマウスに至るまで あらゆる種で保たれています

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