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Updated: Mar 21, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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560の乳がん全ゲノム配列における体内変異の風景

Serena Nik-Zainal1,2, Helen Davies1, Johan Staaf3

  • 1Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

Nature
|May 3, 2016
PubMed
まとめ

この研究では 560の乳がんを分析し 93のがん遺伝子に 駆動変異があり DNA修復の欠陥に関連した 新しい変異シグネチャを発見し 乳がんの遺伝学に関する理解を深めました

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