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Updated: Jan 19, 2026

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構成選択によるA2AアデノシンGタンパク質結合受容体の活性化

Libin Ye1,2, Ned Van Eps2, Marco Zimmer2,3

  • 1Department of Chemistry, University of Toronto, UTM, 3359 Mississauga Road North, Mississauga, Ontario L5L 1C6, Canada.

Nature
|May 5, 2016
PubMed
まとめ

研究者はフッ素-19核磁気共鳴を用いてアデノシンA2A受容体 (A2AR) を研究した. 彼らは4つの異なる受容体状態を特定し,異なるリガンドがGタンパク質結合受容体と結合し,活性化することを明らかにし,薬の発見に不可欠です.

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