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Updated: Mar 21, 2026

Author Spotlight: A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development
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Author Spotlight: A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development

Published on: August 25, 2023

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ヒトステロールトランスポーター ABCG5/ABCG8の結晶構造

Jyh-Yeuan Lee1, Lisa N Kinch2,3,4, Dominika M Borek2,3

  • 1Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

Nature
|May 5, 2016
PubMed
まとめ

ATP結合カセット (ABC) G5/G8トランスポーター構造は,ステロルを排泄する方法を示しています. この発見は,トランスポーター変異によって引き起こされる疾患であるサイトステロレミアを理解するための枠組みを提供します.

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