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Updated: Mar 21, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

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がん新抗原をドナー由来T細胞受容体レパートリーで標的にする

Erlend Strønen1, Mireille Toebes2, Sander Kelderman2

  • 1Department of Cancer Immunology, Oslo University Hospital Radiumhospitalet, Oslo, Norway. K. G. Jebsen Centers for Cancer Immunotherapy and for Inflammation Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.

Science (New York, N.Y.)
|May 21, 2016
PubMed
まとめ

健康なドナーのT細胞は 患者が見逃した癌の新抗原を 認識できます この発見は,腫瘍を効果的に標的にするために"アウトソーシング"免疫反応を使用して,がん免疫療法の新しい戦略を提供します.

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