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Updated: Mar 20, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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高次組成の構造と動態:アミロイド,シグナルソーム,および粒

Hao Wu1, Monika Fuxreiter2

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.

Cell
|May 21, 2016
PubMed
まとめ

この研究は,アミロイドやシグナルソームのような複雑な生物学的組成を理解するための統一モデルを提案しています. タンパク質の領域,モチーフ,そして無秩序な領域の相互作用が 病気でも構造とダイナミクスを支配することを示唆しています

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